Scientists Shatter 100-Year-Old Chemistry Rule, Create "Impossible" Molecules
Science
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Moneycontrol•23-01-2026, 16:24
Scientists Shatter 100-Year-Old Chemistry Rule, Create "Impossible" Molecules
- •UCLA scientists, led by Professor Neil Garg, have successfully challenged Bredt's Rule, a fundamental principle in organic chemistry for nearly a century.
- •They created molecules like cubene and quadricyclene, previously considered impossible due to their highly strained double bonds in bridgehead positions.
- •The breakthrough demonstrates that double bonds can exist and briefly survive in restricted, unusual three-dimensional shapes under controlled conditions.
- •This discovery opens new avenues for molecular design, potentially impacting drug discovery, pharmaceutical research, and the development of novel materials.
- •The research, published in a leading chemistry journal, involved advanced simulations and laboratory experiments, stunning chemists worldwide.
Why It Matters: Scientists at UCLA defied a century-old chemistry rule, creating "impossible" molecules and revolutionizing molecular design.
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